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- Nucleic acids produced upon viral replication, in particular, ligate TLR8 and 926, 27result in the activation of innate immunity and the production of multiple cytokines, amongst which interferon-lambda (IFN-) plays a pivotal role in limiting viral replication and the infection of target cells28
- S i9000
- HLA peptides were analyzed by LC-MS
- In turn, this inhibition prevented the phosphorylation, ubiquitination and subsequent degradation from the IB regulatory complex leading to reduced translocation of NF-B complex to the nucleus
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