When PLT-BMDMs and control BMDMs were stimulated with LPS for 24 h, the expression level of in PLT-BMDMs was found to be 7-fold higher than that in control BMDMs, in association with lower (~10%) expression of (Fig 4A)

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When PLT-BMDMs and control BMDMs were stimulated with LPS for 24 h, the expression level of in PLT-BMDMs was found to be 7-fold higher than that in control BMDMs, in association with lower (~10%) expression of (Fig 4A). BMDMs were also cultured with Corin 0.5 U/mL thrombin, 20 M ADP, 2 g/mL collagen, or unstimulated […]


Cytoplasmic HuR expression is definitely a prognostic element in intrusive ductal breast carcinoma

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Cytoplasmic HuR expression is definitely a prognostic element in intrusive ductal breast carcinoma. ribosome admittance site (IRES) inside the caspase-2-5?UTR. Luciferase activity was suppressed either by chemotherapeutic medicines or ectopic manifestation of HuR. IRES-driven luciferase activity was considerably improved upon siRNA-mediated knockdown of HuR implicating an inhibitory aftereffect of HuR on caspase-2 translation which can […]