Steroids and IVIG might stop the SAg-triggered activity

jamha April 30, 2022 0 Comments

Steroids and IVIG might stop the SAg-triggered activity. 1 SARS-CoV-2 spike superantigen (SAg)-like theme exposure and immune system activation pursuing SARS-CoV-2 infection possibly qualified prospects to hyperinflammation in MIS-C and cytokine surprise. A, Schematic representation from the discussion between SARS-CoV-2 spike and sponsor cell ACE2 receptor (in the bottom). B, Publicity from the SAg-like area […]

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These data suggest, CD8+ T cells may play an overall regulatory role in the context of immune thrombocytopenia and enhance the therapeutic effect of DEX treatment

jamha September 6, 2021 0 Comments

These data suggest, CD8+ T cells may play an overall regulatory role in the context of immune thrombocytopenia and enhance the therapeutic effect of DEX treatment. dexamethasone (DEX) treatment selectively expanded CD8+ Tregs while decreasing CTLs. In vitro coculture studies revealed CD8+ Tregs suppressed CD4+ and CD19+ proliferation, platelet-associated immunoglobulin G generation, CTL cytotoxicity, platelet […]

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