RPMI8226 cells were pretreated with DMSO or z-IETD-fmk (40 M) for 30 min and then treated with DMSO or Len (10 M) for 48 h

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RPMI8226 cells were pretreated with DMSO or z-IETD-fmk (40 M) for 30 min and then treated with DMSO or Len (10 M) for 48 h. activity of lenalidomide (Len) by impairing CRBN cleavage, leading to the attenuated IKZF1 and IKZF3 protein levels and the reduced viability of myeloma cell lines and main myeloma cells from […]